000			01796nam a22001937a 4500
005			20250618121756.0
020			_a9780521785792
082			_a572.8/ _bVOI
100			_aVoit,E.O.
245			_aComputational Analysis of Biochemical Systems: _bA Practical Guide for Biochemists and Molecular Biologists
250			_a1
260			_aSpain _b Cambridge University Press _c2000
300			_axii,531 _ePB
500			_aIN_75 _b2025-05-02
505			_aBiochemical
520			_aThroughout the foreseeable future, research in medicine, molecular biology, and biotechnology will be dominated by scientific advances resulting from the Human Genome Project. Knowledge of genomes will elucidate disease patterns and promise improved and personalized treatments. Food and drug development will be revolutionized by focused manipulation of genes and biochemical processes. Researchers will begin to construct metabolic pathways from scratch. A true understanding of genetic and metabolic function and design will depend on mathematical and computational methods for analyzing biochemical systems. It will require new ways of thinking and novel approaches of integrative analysis. This book teaches biochemists and molecular biologists the use of modern computational methods for the analysis of complex biomedical systems without assuming more than a modest background in mathematics. The book begins with representations of biochemical systems, provides guidelines for setting up models, discusses in detail mathematical and computational methods of parameter estimation and model analysis, and ultimately connects to the modern literature with four detailed case studies. Every step is illustrated with examples and explored with accompanying software.
650			_aBiochemistry
942			_cBK
999			_c226229 _d226229